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Single-cell combined transcriptome explores the molecular mechanism of purine metabolism in keloids | Synapse
March 3, 2026
Single-cell combined transcriptome explores the molecular mechanism of purine metabolism in keloids
BS
Bendian Song
SG
Shitong Guo
ZL
Zhiyu Li
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Key Points
Purine metabolism plays a key role in the cellular processes of keloids, demonstrating significant alterations.
The study identifies specific pathways and gene expressions linked to keloid formation and development.
Single-cell transcriptome analysis provides detailed insights into the diverse cellular mechanisms in keloids.
Understanding these mechanisms may hint at potential therapeutic strategies for managing keloid scars.
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Song et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76662badf0bb9e87dccf7
https://doi.org/https://doi.org/10.1016/j.burns.2026.107895