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A conserved gut-brain axis underlies the neurobehavioral toxicity of a high-sugar diet: A mechanistic study in Drosophila | Synapse
March 3, 2026
A conserved gut-brain axis underlies the neurobehavioral toxicity of a high-sugar diet: A mechanistic study in Drosophila
CY
Chenyi Yu
YH
Yingxia Hu
XZ
Xinyi Zhou
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Key Points
Neurobehavioral toxicity is associated with a high-sugar diet, impacting behavior and physiology.
Key metrics include alterations in neurotransmitter levels that reveal the underlying mechanisms.
Mechanistic study using Drosophila as a model organism to assess how diet affects brain function.
Findings highlight the significance of the gut-brain axis in understanding diet-induced behavioral changes.
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Yu et al. (Mon,) studied this question.
synapsesocial.com/papers/69a76684badf0bb9e87dd50c
https://doi.org/https://doi.org/10.1016/j.cbpc.2026.110472