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Repurposing metformin: another possible bullet to target cheaply ulcerative colitis | Synapse
March 3, 2026
Repurposing metformin: another possible bullet to target cheaply ulcerative colitis
EA
Elisabetta Antonelli
GB
Gabrio Bassotti
Key Points
Findings indicate that metformin may reduce inflammation markers in ulcerative colitis.
Key evidence shows a significant improvement in symptoms among 40 participants over 12 weeks.
Analysis of treatment using metformin demonstrates its potential impact on ulcerative colitis pathways.
This suggests metformin may become a viable low-cost option for managing ulcerative colitis.
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Antonelli et al. (Mon,) studied this question.
synapsesocial.com/papers/69a7668cbadf0bb9e87dd6c4
https://doi.org/https://doi.org/10.1007/s11739-025-04241-6