SLC6A6 imports taurine into mitochondria to sustain mitochondrial translation and tumour growth

Key Points

• Taurine import by SLC6A6 supports mitochondrial translation, promoting cell growth, and proliferation.
• Findings show that disrupting SLC6A6 impairs mitochondrial functions and reduces tumour growth in vitro by around 50%.
• Analysis of cellular models identifies the role of SLC6A6 in taurine transport and its critical function in mitochondrial health.
• These insights may highlight new therapeutic avenues targeting metabolic pathways in cancer treatment.