March 3, 2026Open Access

Anti-obesity effects of Withania somnifera and Chrysanthemum zawadskii Herbich var. latilobum (Maxim.) Kitamura by regulating lipid metabolism and insulin signaling in 3T3-L1 adipocytes

Key Points

These findings show that ASC modulates insulin signaling and other pathways in adipocytes to combat obesity.
ASC effectively influences adipogenesis, lipogenesis, and lipolysis, promoting healthier energy metabolism.
Analysis of metabolic pathways reveals significant benefits of ASC for managing obesity in adipocytes from 3T3-L1 cells.
This work highlights ASC's potential as a therapeutic option for obesity, warranting further investigation in clinical settings.

Abstract

These findings demonstrate that ASC effectively modulates multiple metabolic pathways in adipocytes, including adipogenesis, lipogenesis, lipolysis, energy metabolism, and insulin signaling, to exert its anti-obesity effects.

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Cite This Study

Park et al. (Thu,) studied this question.

synapsesocial.com/papers/69a7675ebadf0bb9e87e0ab6 https://doi.org/https://doi.org/10.4162/nrp.2026.20.1.3

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