Aqueous fruit peel extract of Dillenia indica alleviates alpha-naphthyl isothiocyanate-induced acute cholestatic liver injury in mice

Key Points

• Cholestatic liver injury was significantly reduced in mice treated with Dillenia indica extract—indicating its therapeutic potential.
• The treatment led to improved liver function markers by 40% compared to untreated controls, highlighting its efficacy.
• Administration involved applying an aqueous extract of Dillenia indica to assess its protective impact on liver injury induced by alpha-naphthyl isothiocyanate.
• The findings may enable further exploration of this natural extract's application in liver disease management, emphasizing preclinical validation.