Differential toxicity of perfluorooctane sulfonate (PFOS) in wild-type and Oatp1d1 mutant zebrafish larvae

Key Points

• PFOS toxicity varies significantly between wild-type and mutant zebrafish larvae, highlighting genetic effects.
• The study observed differences in toxic response rates, with Oatp1d1 mutants exhibiting a higher susceptibility to PFOS exposure.
• Assessment included both wild-type and mutant zebrafish larvae subjected to varying concentrations of PFOS.
• These findings suggest the need for further investigation into genetic factors influencing chemical toxicity in aquatic species.