Diallyl disulfide suppresses weight gain, adipogenesis, and matrix metalloproteinases (MMPs) expression in high-fat-diet-induced obese animal model

Key Points

• Weight gain is significantly suppressed by diallyl disulfide, impacting adipogenesis.
• Diallyl disulfide appears to inhibit both MMP-2 and MMP-9, which are associated with fat accumulation.
• Observational analysis in a high-fat diet-induced obesity model shows the effects in mice.
• These findings suggest potential therapeutic benefits in managing obesity-related conditions.