The expression pattern and prognostic relevance of p120-catenin, COL4A2 and SOX10 in glioma

Key Points

• Glioma prognosis may be influenced by the expression levels of p120-catenin, COL4A2, and SOX10, potentially linking these factors to tumor behavior.
• The presence of p120-catenin suggests a tumor-promoting role while COL4A2 and SOX10 indicate tumor suppression, highlighting their opposing functions.
• Observational analysis of glioma cases shows variations in prognostic markers tied to gender, particularly SOX10 in female GBM patients.
• Understanding these expression patterns could inform future therapeutic approaches; further validation in diverse cohorts is necessary.