Whole genome sequencing data analysis identified a cefotaxime-resistant Empedobacter brevis GBW-1 isolate from ground beef encoding a novel metallo-beta-lactamase variant, blaEBR-6

Key Points

• Cefotaxime-resistance was identified in an isolate of Empedobacter brevis from ground beef, posing food safety risks.
• A new variant of metallo-beta-lactamase, blaEBR-6, was characterized, which can degrade common antibiotics.
• Whole genome sequencing was applied to understand the genetic basis of the cefotaxime resistance in the bacteria.
• Such findings may enhance surveillance measures for antibiotic-resistant bacteria in food products.