ZNF16 inhibits PEDV replication through autophagy-mediated degradation of S1 protein

Key Points

• ZNF16 significantly inhibits PEDV replication in vitro, emphasizing its role in viral control.
• Inhibition leads to reduced levels of S1 protein, demonstrating ZNF16's effectiveness in this process.
• Analysis identifies the autophagy pathway as a critical mechanism in ZNF16's antiviral action.
• The findings support ZNF16 as a potential target for developing antiviral strategies against PEDV.