Impact of gender differences on prognosis in patients with acute cerebral infarction associated with REM-related obstructive sleep apnea: a retrospective cohort study

Key Points

• Female patients with acute cerebral infarction and REM-related obstructive sleep apnea experience poorer outcomes compared to males, highlighting a significant gender effect.
• Severe REM hypoxia and inflammation are likely contributors to this adverse prognosis, necessitating focused attention on female patients.
• The study employs a retrospective cohort design to examine the impact of gender on outcomes in patients suffering from REM-related obstructive sleep apnea.
• These findings support the need for tailored screening and intervention approaches based on gender to improve overall care in this population.