Targeted delivery of venetoclax-encapsulated human heavy chain ferritin nanoparticles in acute myeloid leukemia

Key Points

• Targeted delivery significantly enhances therapy effectiveness against acute myeloid leukemia.
• A notable improvement in drug accumulation was observed, reporting a 75% increase in drug delivery efficiency.
• The approach utilized ferritin nanoparticles to encapsulate venetoclax, ensuring precise targeting to cancer cells.
• Overall, the findings may enable better treatment strategies, but require external validation for clinical use.