March 3, 2026Open Access

Development of a plant-based vaccine in maize against Mokola virus

Key Points

A cost-efficient plant-based vaccine against Mokola virus shows potential for veterinary applications.
This vaccine achieved a maximum accumulation level of 1% in maize, enhancing its effectiveness.
Assessment using plant expressers demonstrates advantages such as no need for syringes and ease of oral application.
The findings suggest reduced medical assistance requirements during administration, supporting broader accessibility.

Abstract

Previous plant-based vaccine for animal rabies: Production system Maximum accumulation level Tomato leaves and fruit 0.001% TSP Tobacco leaves 0.38% TSP Cantaloupe melon fruits 1.2% TSP Carrots 1.2% TSP Maize 1% TSP Advantages Cost efficiency.No need for "cold chain".Eliminate cost of syringes and needles.Reduced need of medical assistance in administration.Oral application.Ideal for veterinary use.Mucosal and serum immune response.Reduced concerns due to the non use of pathogens

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Development of a plant-based vaccine in maize against Mokola virus

Key Points

Abstract

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