Correction Paschou et al., Dysregulated proteostasis in p.A53T-α-Synuclein astrocytes aggravates Lewy-like neuropathology in a Parkinson’s disease iPSC model | Synapse
March 3, 2026Open Access
Correction Paschou et al., Dysregulated proteostasis in p.A53T-α-Synuclein astrocytes aggravates Lewy-like neuropathology in a Parkinson’s disease iPSC model
Key Points
Neuropathology worsens significantly due to dysregulated proteostasis in astrocytes.
Findings highlight a connection between p.A53T-α-synuclein and increased Lewy-like features.
Analysis uses an induced pluripotent stem cell model specifically for Parkinson’s disease.
Highlights the need for targeted interventions in astrocyte function in Parkinson’s disease.