Synthesis and antiprotozoal activity of β-carboline-(piperazinyl)-1,3,5-triazine hybrids

Key Points

• The hybrids show notable antiprotozoal activity against target protozoa, highlighting their potential use as drug candidates.
• In vitro tests revealed that specific hybrids exhibited up to 85% inhibition of protozoal growth, a promising result for drug development.
• Synthesis involved combining β-carboline with piperazinyl and triazine, resulting in novel chemical compounds that could treat infections.
• These findings suggest that further exploration of these hybrids may lead to effective treatments for protozoan infections, potentially impacting public health.