Ivabradine in pediatric cardiac patients induces three hemodynamic phases: initial HR decrease with stable oxygen delivery, followed by HR increase with worsened delivery, then HR decrease with improv
What are the acute hemodynamic effects of ivabradine in pediatric cardiac critical care patients?
Ivabradine produces a triphasic hemodynamic response in pediatric cardiac critical care patients, ultimately decreasing heart rate and improving systemic oxygen delivery.
Absolute Event Rate: 0% vs 0%
Ivabradine seems safe in pediatric patients. It is associated with 3 distinct hemodynamic response phases: the first phase is associated with decreased heart rate and unchanged systemic oxygen delivery, the second phase is associated with increased heart rate and worsened systemic oxygen delivery, and the third phase being associated with decreased heart rate and improved systemic oxygen delivery. These phases coincide with the pharmacokinetic properties of ivabradine.
Loomba et al. (Mon,) reported a other. Ivabradine in pediatric cardiac patients induces three hemodynamic phases: initial HR decrease with stable oxygen delivery, followed by HR increase with worsened delivery, then HR decrease with improv.