Halogen Atom Transfer-Induced Radical Cascades Cyclization of N-(o-Cyanobiaryl)acrylamides with Alkyl Halides via Boryl Radical-Mediated

Key Points

• The central aim is to explore boryl radical techniques for synthesizing polycyclic nitrogen compounds using an XAT strategy.
• Utilized ligated boryl radicals under photocatalytic conditions
• Implemented halogen-atom transfer for cyclization
• Synthesis focused on N-(o-Cyanobiaryl)acrylamides with alkyl halides
• Successfully synthesized nitrogen-containing polycyclic compounds
• Demonstrated efficiency of the boryl radical-mediated approach through XAT
• Achieved high selectivity for cyclization products