Effects of combined phytosterols and phospholipids on blood lipids and the fluidity and lipid profiles of the erythrocyte membrane in individuals with borderline hyperlipidemia: a double-blinded randomized controlled trial

Key Points

• This research aims to evaluate the effects of combined phytosterols and phospholipids on blood lipids and erythrocyte membrane characteristics.
• Conducted a double-blinded randomized controlled trial
• Administered interventions over a 60-day period
• Monitored changes in total cholesterol (TC) and ApoB levels
• Assessed erythrocyte lipid profiles through lipidomics
• Significant decreases in total cholesterol and ApoB in the combined phytosterols and phospholipids group
• Notable reduction in total cholesterol in the phytosterols-only group
• Erythrocyte lipidomic analysis correlated blood lipids with membrane lipids