Cu(I)-catalyzed, N-Fluorobenzamides Enabling 1,2-Carbofluorination of Unactivated Alkenes via Free Radical Relay

Key Points

• The aim is to develop a method for creating carbon-fluorine bonds using a free radical approach.
• Utilized Cu(I) as a catalyst for the reaction
• Employed N-fluorobenzamide as a reactant
• Focused on the bifunctionalization of unactivated alkenes
• Successfully formed carbon-fluorine bonds in unactivated alkenes
• Demonstrated the effectiveness of free radical relay in acarbon-fluorine formation
• Revealed the potential for broad application in organic synthesis