Validation of PaO2:FiO2 for predicting hospital mortality in critically ill patients with acute hypoxaemic respiratory failure: a retrospective binational registry-based study

Key Points

• The study aims to identify the best PaO2:FiO2 threshold within the first 24 hours of ICU admission for predicting mortality.
• Analyzed data from a bi-national registry of adult patients in Australia and New Zealand
• Focused on patients admitted from January 2018 to December 2022
• Determined discriminatory capacity of various PaO2:FiO2 thresholds
• Identified a critical PaO2:FiO2 threshold for mortality prediction
• Demonstrated improved prognostication in critically ill patients
• Provided data supporting ICU admission protocols