Mitochondria-Targeted NIR-II Organic Probes for Imaging–Guided Photodynamic Therapy

Key Points

• The aim is to develop mitochondria-targeted organic probes for enhanced photodynamic therapy in cancer.
• Developed organic probes for NIR-II fluorescence imaging.
• Evaluated imaging capabilities in tumor tissues.
• Assessed the effectiveness of photodynamic therapy using these probes.
• Probes demonstrated superior tumor imaging with enhanced penetration over traditional photosensitizers.
• Achieved effective photodynamic therapy with reduced side effects in targeted areas.