What question did this study set out to answer?

This research aims to determine if CT-defined emphysema morphology can predict histological subtypes of lung cancer.

March 5, 2026Thoracic research and practice1 citationsOpen Access

CT-defined Emphysema Morphology as a Predictor for Histological Subtypes of Lung Cancer: A Single-center Retrospective Study

FAFadlan Adima Adrianta DEDini Rachma Erawati SPSuryanti Dwi Pratiwi

Key Points

This research aims to determine if CT-defined emphysema morphology can predict histological subtypes of lung cancer.
Conducted a single-center retrospective study
Analyzed CT scans to assess emphysema morphology
Matched findings with histological data on lung cancer subtypes
CT-defined emphysema morphology is associated with lung adenocarcinoma (ADC)
Emphysema volume does not predict lung ADC
Emphysema morphology shows potential as a non-invasive imaging biomarker for risk assessment

Abstract

CT-defined CLE is independently associated with lung ADC, whereas emphysema volume is not predictive of lung ADC. Emphysema morphology may serve as a non-invasive imaging biomarker to support histological risk stratification when tissue diagnosis is limited.

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Cite This Study

Adrianta et al. (Tue,) studied this question.

synapsesocial.com/papers/69a91da8d6127c7a504c0b0b https://doi.org/https://doi.org/10.4274/thoracrespract.2026.2025-9-6

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