What question did this study set out to answer?

To evaluate the role of central and peripheral neuromodulators in treating functional dyspepsia and gastroparesis with a focus on symptoms.

March 5, 20260 citations

Central and Peripheral Neuromodulators in Functional Dyspepsia and Gastroparesis: A Symptom-Based Clinical Review.

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IHIgnacio Hanna-Jairala JTJan Tack MWM. Weinberger

Key Points

To evaluate the role of central and peripheral neuromodulators in treating functional dyspepsia and gastroparesis with a focus on symptoms.
Clinical review of existing literature on neuromodulators in FD and GP
Evaluation of symptom-based treatment outcomes
Assessment of current evidence quality
Neuromodulators may improve symptoms of functional dyspepsia and gastroparesis
A symptom-oriented approach may optimize patient outcomes
There is a need for high-quality, subtype-specific trials to support findings

Abstract

Neuromodulators provide a rational, mechanism-based treatment option for FD and GP, and a symptom-oriented approach may optimize patient outcomes; although high-quality, subtype-specific trials are needed to strengthen the evidence base.

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Central and Peripheral Neuromodulators in Functional Dyspepsia and Gastroparesis: A Symptom-Based Clinical Review.

Key Points

Abstract

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