Obesity as a Determinant of Periodontal Therapy Outcomes: Insights on Oxidative and Endoplasmic Reticulum Stress Pathways

This study reinforces the importance of periodontal care providers in the early identification of patients at increased risk of suboptimal periodontal healing. Obesity and systemic inflammatory burden emerge as relevant modifiers of treatment response, indicating that periodontal outcomes are influenced by factors beyond the oral cavity. Incorporating simple clinical information, such as blood pressure and inflammatory status, into routine periodontal assessment would support more individualized treatment planning, optimize follow-up strategies, and improve long-term outcomes in patients with chronic periodontitis.