To develop and evaluate a smart injectable hydrogel for repairing spinal cord injuries by targeting reactive oxygen species.
Preparation of MgMn-LDH/GPH hydrogels
Assessment of hydrogel properties
Evaluation of effectiveness in spinal cord repair
Analysis of the microenvironment changes during repair
Effective ROS-scavenging capabilities observed in the hydrogel
Significant oxygen generation in the injury site
Improved healing and functional recovery in the spinal cord
Abstract
Scheme of the preparation of MgMn-LDH/GPH hydrogels and the spinal cord injury (SCI) repair process. (A) Preparation process of MgMn-LDH/GPH hydrogels; (B) spinal cord injury (SCI) repair process.