High-throughput single-cell proteomics and transcriptomics from same cells with a nanoliter-scale, spin-transfer approach

Key Points

• This research aims to enhance our understanding of cellular diversity and function by integrating proteomics and transcriptomics at the single-cell level.
• Utilized a high-throughput single-cell multiomic platform.
• Employed a nanoliter-scale approach for sample processing.
• Analysed both proteomic and transcriptomic data from individual cells.
• Identified distinct cellular states through multiomic profiling.
• Provided insights into the regulatory roles of biomolecular networks.
• Enhanced sensitivity and specificity in detecting protein and RNA expression levels.