The aim is to assess the impact of expanding the in situ hybridization (ISH) panel on detecting high-risk HPV genotypes in anal biopsies.
Expanded ISH panel from 7 to 18 genotypes
Conducted analysis on anal biopsies
Identified presence of high-risk HPV in both HSIL and non-HSIL cases
Improved detection rates of high-risk HPV in anal HSIL cases
Identified additional high-risk HPV cases in patients without HSIL
Abstract
Expansion of the ISH panel from 7 to 18 genotypes improved detection for high-risk HPV in anal HSIL and identified high-risk HPV in additional patients without HSIL.