Patients with cerebrovascular disease who died within 1 month had a significantly higher median EASIX score of 2.90 vs. 0.80 in survivors (P < .001).
Does the EASIX score predict 1-month mortality in patients with cerebrovascular disease?
The EASIX score is significantly elevated in cerebrovascular disease patients who die within 1 month, suggesting its potential utility as a prognostic biomarker in the emergency department.
Absolute Event Rate: 0% vs 0%
Abstract Introduction Cerebrovascular disease (CVD) represents a major global health concern that affects the blood vessels throughout the body and contributes to a considerable burden of mortality and morbidity. The Endothelial Activation and Stress Index (EASIX) has recently emerged as a promising biomarker for predicting many disease complications and outcomes. We aimed to investigate the relationship between EASIX and disease mortality in patients with CVD. Methods The present study was conducted in a tertiary emergency department between January 6, 2023, and January 6, 2024, who were diagnosed with CVD. The mortality rate among patients within a 1-month period was analyzed. The EASIX was calculated using lactate dehydrogenase level (U/L) × creatinine level (mg/dL)/platelet count (×109/L). The parameters were then compared in relation to disease morbidity. Results Following the exclusion of patients who met the preestablished exclusion criteria, the study included 74 participants. In the 1-month follow-up of 64 patients, no mortality was observed. The median EASIX score was 0.80 (IQR, 0.5-2.2) in the surviving patients, while the median EASIX score was 2.90 (IQR, 1.00-10.55) in the patients who died, indicating a statistically significantly higher score (P .001). Discussion EASIX has the potential to be a prognostic marker for mortality in patients with CVD.
Zortuk et al. (Tue,) reported a other. Patients with cerebrovascular disease who died within 1 month had a significantly higher median EASIX score of 2.90 vs. 0.80 in survivors (P < .001).