Dual-utility ctDNA in diffuse large B-cell lymphoma: integrated genotyping unveils minimal residual disease dynamics and subtype-specific clonal evolution

Key Points

• This research aims to highlight how ctDNA can improve prognosis and reveal the dynamics of DLBCL disease subtypes.
• Utilized ctDNA analysis to assess minimal residual disease
• Integrated genotyping to study clonal evolution
• Focused on diffuse large B-cell lymphoma cases
• Demonstrated ctDNA's effectiveness in prognostic stratification
• Revealed subtype-specific clonal evolution dynamics
• Support for tailored treatment approaches based on ctDNA findings