Clonal haematopoiesis in chronic lymphocytic leukaemia: Biology, inflammaging and clinical implications in the era of targeted therapy.

Key Points

• This research aims to explore the impact of clonal haematopoiesis on chronic lymphocytic leukaemia prognosis and treatment outcomes.
• Examined the role of clonal haematopoiesis in chronic lymphocytic leukaemia
• Analyzed effects of clonal haematopoiesis on treatment-related toxicities and cardiovascular risk
• Compared outcomes of targeted therapies versus traditional chemoimmunotherapy
• Clonal haematopoiesis is prevalent among chronic lymphocytic leukaemia patients
• It affects overall prognosis and may increase treatment-related toxicities and cardiovascular risk
• Targeted therapies may lessen certain adverse effects associated with clonal haematopoiesis

Abstract