What does this research mean for the field?

Exoenzymes-encoding genes are associated with drug resistance in multidrug resistant Pseudomonas aeruginosa. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This research aims to investigate the prevalence of virulence and carbapenemase genes in multidrug resistant Pseudomonas aeruginosa isolates.

March 8, 2026Open Access

Occurrence of virulence genes and carbapenemase genes in multidrug resistant clinical isolates of Pseudomonas aeruginosa

Key Points

This research aims to investigate the prevalence of virulence and carbapenemase genes in multidrug resistant Pseudomonas aeruginosa isolates.
Analyzed clinical isolates of Pseudomonas aeruginosa from various infections.
Compared the presence of virulence and carbapenemase genes between multidrug resistant and drug-susceptible isolates.
Assessed the relation of virulence genes across different infection types, such as wounds and urinary tract infections (UTIs).
Multidrug resistant strains exhibited more virulence genes than drug-susceptible ones.
Higher prevalence of virulence genes was found in wound isolates compared to UTI isolates.

Abstract

The misuse/overuse of antibiotics, poor hygiene, and errors of health care personnel were the main factors that significantly increased the prevalence of MDR P. aeruginosa. Hospitals should craft and implement a specific control strategy to reduce the distribution of MDR P. aeruginosa. The MDR isolates expressed exoenzymes-encoding genes as compared to the drug-susceptible isolates. The prevalence of these virulence genes was higher in wound isolates as compared to UTIs. This study indicates that exoenzymes-encoding genes are associated with drug resistance in P. aeruginosa.

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Discussion

Authors

Hira Ahsan

Bilal Aslam

Zeeshan Nawaz

Journals

The Journal of Infection in Developing Countries

Actions

Institutions

King Saud University

University of Agriculture Faisalabad

Government College University, Faisalabad

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Occurrence of virulence genes and carbapenemase genes in multidrug resistant clinical isolates of Pseudomonas aeruginosa

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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