Clopidogrel modulate deregulated metabolic pathways in cuprizone fed mice model of Multiple Sclerosis

Key Result

Clopidogrel modulated deregulated metabolic pathways in a cuprizone-fed mouse model of multiple sclerosis.

Key Points

• The research aims to examine how clopidogrel affects disrupted metabolic pathways in a model of multiple sclerosis.
• Utilized a cuprizone-fed mouse model to simulate multiple sclerosis.
• Analyzed transcriptomic datasets to identify metabolic alterations influenced by clopidogrel treatment.
• Clopidogrel treatment significantly modulated several metabolic pathways.
• Marked improvements in demyelination markers were observed post-treatment.