Artificial intelligence and machine learning show promise in transforming fibromuscular dysplasia diagnosis, risk stratification, and management, despite limited large-scale validation.
AI and ML have the potential to transform the diagnosis and management of fibromuscular dysplasia, though real-world implementation faces data and regulatory challenges.
Fibromuscular dysplasia (FMD) is a non-atherosclerotic vascular disorder with heterogeneous presentations, making diagnosis and management highly dependent on imaging and clinical expertise. This narrative review examines how artificial intelligence (AI) and machine learning (ML) are transforming FMD care. AI-enhanced imaging, particularly convolutional neural network-based analysis, improves detection of the characteristic "string-of-beads" pattern on CT angiography, magnetic resonance angiography, and ultrasound, although FMD-specific validation remains limited. ML models facilitate risk stratification, prediction of disease progression, and early identification of complications such as aneurysms and stroke by integrating clinical, imaging, and genomic data. AI-driven clinical decision support systems further enable personalized treatment selection through pharmacogenomic insights and robot-assisted interventions. Despite promising real-world applications, challenges persist, including limited large-scale datasets, workflow integration, regulatory barriers, and algorithmic bias affecting underrepresented populations. Future advances in explainable AI, federated learning, and digital health integration may enable a shift toward predictive, patient-centered FMD management.
Hamza et al. (Fri,) conducted a review in Fibromuscular dysplasia (FMD). Artificial intelligence and machine learning was evaluated. Artificial intelligence and machine learning show promise in transforming fibromuscular dysplasia diagnosis, risk stratification, and management, despite limited large-scale validation.