Six versus five fractions per week (Chemo)-Radiotherapy for locally advanced head and neck squamous cell carcinoma – A nationwide cohort study from the swedish head and neck cancer register

Key Points

• The study aims to evaluate the effectiveness of six versus five fractions of radiotherapy for locally advanced head and neck squamous cell carcinoma.
• Analyzed data from the Swedish head and neck cancer register.
• Compared outcomes between patients receiving six fractions per week versus five.
• Focused on loco-regional control as the primary outcome.
• Moderately accelerated radiotherapy with six fractions improved loco-regional control.
• No significant OS (overall survival) benefit was observed.