Electrochemical cross-dehydrogenative coupling of isochroman with sulfonamide and indole

Key Points

• This research aims to develop an efficient electrochemical method for synthesizing hybrid drug candidates from isochroman and sulfonamides or indoles.
• Developed a cross-dehydrogenative coupling reaction.
• Utilized electrochemical techniques for synthesis.
• Combined two medium-sized backbone molecules.
• Successfully established a novel coupling reaction.
• Demonstrated the efficient formation of hybrid molecular drug candidates.