Introduction. Paragangliomas are rare neuroendocrine tumors that arise from cells originating in the neural crest. They are usually benign, but may show malignant behavior. Aim of the study. To present the clinical experience of the Otorhinolaryngology Department of the Nicolae Testemițanu State University of Medicine and Pharmacy, based at the Timofei Moșneag Republican Clinical Hospital, Chișinău, Republic of Moldova, in the management of paragangliomas, and to review the medical literature in order to increase awareness among ENT specialists. Methodology. A retrospective study was performed between 2020 and 2024, including patients with type A and type B temporal bone paragangliomas, with atypical clinical course and diagnostic and therapeutic challenges. A review of the relevant literature was also conducted to support the analysis and conclusions. Results. Surgical treatment of type A and B temporal bone paragangliomas achieved good tumor control, with fewer postoperative complications and a clear improvement of the quality of life. The study emphasized the importance of accurate differential diagnosis and appropriate diagnostic methods in choosing the correct treatment strategy, improving survival, reducing hospital costs, and lowering intraoperative and postoperative complications. Conclusions. Although significant progress has been made in diagnosis and treatment, paragangliomas remain a challenging condition in otorhinolaryngology, as their clinical presentation often overlaps with that of other diseases.
Ursachi et al. (Thu,) studied this question.
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