The current study focuses on evaluating the physicochemical properties and biological activities of Euphorbia guyoniana Boiss. & Reut. latex. This included estimating the total carbohydrate, lipid, and protein content, as well as detecting phenolic compounds using high-performance liquid chromatography. Also, antioxidant activity was assessed by measuring total antioxidant capacity and hydroxyl radical capture. Furthermore, antibacterial activity was determined by measuring the minimum inhibitory concentration and calculating the sun protection factor. The results demonstrated promising biological and pharmacological potential for the latex from E. guyoniana, revealing a rich chemical diversity and high carbohydrate, lipid, and protein content estimated at 194.79 ? 0.020 mg glucose equivalent/g latex, 170.48 ? 0.025 mg soybean oil equivalent/g latex, and 71.51 ? 0.031 mg bovine serum albumin equivalent /g latex. The extract also revealed a range of phenolic compounds, including chlorogenic acid, naringin, and quercetin. Further-more, the extract exhibited good antioxidant activity, expressed in the total antioxidant capacity assay as 63.89 ? 0.003 mg ascorbic acid equivalent/g latex. Also, hydroxyl radical capture compared to the reference standard ascorbic acid as IC50 88.81 ? 3.50 mg/mL and 0.083 ? 0.013 mg/mL, respectively. Furthermore, E. guyoniana latex exhibited strong antibacterial activity against six pathogenic strains at 0.9375 mg/mL. It also demonstrated moderate sun protection factor, compared to a-tocopherol, estimated at 14.9 and 16.29, respectively. In conclusion, these results provide strong scientific support for the use of E. guyoniana latex as a natural plant source with diverse biological and pharmacological properties.
Segueni et al. (Thu,) studied this question.