Establishment of Reference Intervals for Plasma TSH Across the Lifespan in an Algerian Mediterranean Population

Key Points

• The aim is to create age-specific reference intervals for plasma TSH in an Algerian population.
• Conducted a cross-sectional analysis in Algeria
• Measured plasma TSH levels across different age groups
• Examined the influence of age and sex on TSH levels
• Identified age as the primary factor affecting TSH levels
• Sex-related variations in TSH were not clinically significant
• Established the first local age-specific TSH reference intervals for diagnostic use