Unveiling Endotypes in Systemic Lupus Erythematosus Through Multi‐Omic Analysis: Insights into Cardiovascular and Renal Complications | Synapse
March 12, 2026
Unveiling Endotypes in Systemic Lupus Erythematosus Through Multi‐Omic Analysis: Insights into Cardiovascular and Renal Complications
Key Points
The aim is to identify molecular endotypes in systemic lupus erythematosus using multi-omic analysis.
Conducted multi-omic profiling of systemic lupus erythematosus samples.
Integrated data from immune, vascular, and metabolic pathways.
Analyzed associations with cardiovascular risk and renal complications.
Identified distinct molecular endotypes within systemic lupus erythematosus.
Found associations between specific endotypes and cardiovascular risk.
Showed links between endotypes and renal complications through multi-omic data.
Abstract
Multi-omic profiling delineates molecular endotypes in SLE integrating immune, vascular, and metabolic pathways associated with CV risk and LN, supporting their potential for precision risk stratification.