Low aortic valve calcium score is associated with increased mortality and advanced symptoms despite fewer complications, while very-high score indicates higher procedural risk and mortality.
Does the Aortic Valve Calcium Score (AVCS) spectrum predict bimodal outcomes in patients undergoing Transcatheter Aortic Valve Implantation?
Aortic valve calcium scoring reveals a bimodal risk distribution in TAVI, where both low AVCS (fibrotic phenotype) and very-high AVCS are associated with increased mortality, suggesting fibrosis assessment should be incorporated into treatment strategies.
Absolute Event Rate: 0% vs 0%
Low AVCS defines a unique phenotype marked by predominant fibrosis, advanced symptoms, and increased mortality despite fewer procedural complications. In contrast, very-high AVCS is linked to higher procedural risk, more bicuspid valves, and increased mortality. These insights challenge calcification-based criteria and support incorporating fibrosis assessment into treatment strategies.
Talmor-Barkan et al. (Tue,) reported a other. Low aortic valve calcium score is associated with increased mortality and advanced symptoms despite fewer complications, while very-high score indicates higher procedural risk and mortality.