Ligand-Enabled Hydrohydrazidation of Alkynes Catalyzed by Unsymmetrical Gold(I)-Thiazol-2-ylidenes

Key Points

• The aim is to develop a selective method for hydrohydrazidation of alkynes using gold(I) catalysts.
• Utilized unsymmetrical gold(I)-thiazol-2-ylidene complexes as catalysts.
• Performed reactions with various alkynes and acyl hydrazines.
• Analyzed selectivity and efficiency of the hydrohydrazidation process.
• Achieved high selectivity for the hydrohydrazidation of alkynes.
• Demonstrated effectiveness of gold(I)-thiazol-2-ylidene catalysts in organic synthesis.
• Reported enhanced yields in the formation of amide derivatives.