Renal outcomes in ANCA-associated vasculitis without clinically apparent kidney involvement: a multicentre REVEAL cohort study

Key Points

• This research investigates the renal outcomes in patients with ANCA-associated vasculitis lacking evident kidney problems.
• Conducted a multicentre cohort study using the REVEAL database.
• Monitored TWA-CRP levels as a marker of inflammation.
• Evaluated eGFR (estimated Glomerular Filtration Rate) for kidney function.
• Found a significant association between elevated TWA-CRP and the development of chronic kidney disease (CKD).
• Recommended eGFR monitoring in patients despite normal urinalysis to catch potential kidney issues early.