Selective Harm Reporting in Inflammatory Sinonasal Trials: A Systematic Review of Registry‐Publication Concordance

Key Points

• To evaluate the consistency of harm reporting in sinonasal trials with clinical trial registry data.
• Conducted a systematic review of sinonasal trials
• Assessed registry-publication concordance for adverse events
• Analyzed the completeness of harm reporting
• Adverse event reporting in publications was found to be incomplete
• Clinical trial registries provided valuable harm-related evidence that was often underused
• Significant discrepancies were observed between registry entries and published results, particularly on adverse events