Acquired Multiple Acyl‐Coenzyme A Dehydrogenase Deficiency Associated With Sertraline in Sweden—A Nationwide Population‐Based Study

Key Points

• This research aims to investigate the association between sertraline use and acquired multiple acyl-CoA dehydrogenase deficiency (MADD) in adults.
• Nationwide population-based study conducted in Sweden
• Focused on adults undergoing treatment with sertraline
• Evaluated incidence of muscle symptoms related to MADD
• Acquired MADD was identified as the most common type of adult-onset MADD in this population
• The condition showed a positive response to riboflavin treatment
• Recommendation for evaluation of muscle symptoms in patients receiving sertraline therapy