What question did this study set out to answer?

The aim is to examine prenatal and postnatal management strategies for congenital long QT syndrome (LQTS) through multiple specialties.

March 13, 2026Open Access

Fetal Long QT Syndrome: Case Series and Literature Review With Focus on Multidisciplinary Care Coordination

Key Result

A multidisciplinary team approach improved prenatal and postnatal outcomes in five cases of fetal long QT syndrome through comprehensive management strategies.

Key Points

The aim is to examine prenatal and postnatal management strategies for congenital long QT syndrome (LQTS) through multiple specialties.
Reviewed five cases of fetal LQTS diagnosis.
Utilized a multidisciplinary team for optimal management.
Implemented various diagnostic strategies and treatment approaches.
Variable initial presentations of LQTS in the five cases were noted.
The multidisciplinary team improved prenatal management.
Well-planned postnatal treatment led to better neonatal and maternal outcomes.

Structured PICO

Population

5 cases of fetal diagnosis of Long QT Syndrome (LQTS)

Intervention

Multidisciplinary team approach including fetal cardiologist, adult and pediatric electrophysiologists, medical physicists, neonatologists, maternal-fetal medicine specialists, fetal cardiac nurse coordinators, and genetic counselors

Outcome

Optimization of neonatal and maternal outcomes

A multidisciplinary approach is essential for the optimal prenatal and postnatal management of fetal Long QT Syndrome.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

Congenital long QT syndrome (LQTS) is a group of heritable conditions that are associated with cardiac repolarization abnormality characterized by QT prolongation on ECG and risk of life‐threatening arrhythmias. Prenatal detection of LQTS presents many challenges for clinicians and a multidisciplinary approach is needed for optimal prenatal and postnatal management. We describe five cases of fetal diagnosis of LQTS with variable initial presentation, diagnostic strategies, and management approaches. A multidisciplinary team approach including fetal cardiologist, adult and pediatric electrophysiologists, medical physicists, neonatologists, maternal–fetal medicine specialists, fetal cardiac nurse coordinators, and genetic counselors allowed for comprehensive prenatal management and well‐planned postnatal treatment to optimize neonatal and maternal outcomes.