The research aims to profile the whole transcriptome and M6A modifications in Parkinson's disease models treated with tDCS.
Conducted RNA-seq to analyze gene expression in PD mouse models.
Utilized M6A-Seq to evaluate methylation patterns in transcripts.
Compared data from PD mice with and without tDCS treatment.
Identified specific changes in gene expression associated with tDCS treatment.
Revealed differential M6A methylation patterns between treated and untreated mice.
Highlighted potential therapeutic targets for Parkinson's disease intervention.
Abstract
This project contains RNA-seq and M6A-Seq data generated from an whole transcriptome profiling experiment in a mouse model of PD with and without tDCS treatment.