Comprehensive circulating tumor DNA mutation profiling via CAPP-Seq liquid biopsy for cervical cancer

Key Points

• The aim is to evaluate the utility of ctDNA mutation profiling in cervical cancer for molecular characterization and monitoring.
• Utilized CAPP-Seq for ctDNA mutation profiling
• Analyzed tumor-associated genomic alterations
• Focused on various histological subtypes of cervical cancer
• Achieved a high detection rate of genomic alterations
• Demonstrated feasibility for minimal invasiveness
• Indicated potential for effective disease monitoring in cervical cancer