c-Myc regulated long noncoding RNA TRD-AS1 to affect the progression of oral squamous cell carcinoma

Key Points

• The study aims to explore how c-Myc regulates the long noncoding RNA TRD-AS1 and its impact on oral squamous cell carcinoma (OSCC).
• Examined the regulation of TRD-AS1 by c-Myc in OSCC cells.
• Assessed the effects of TRD-AS1 on cell migration and proliferation.
• Analyzed changes in tumor metabolism associated with TRD-AS1 expression.
• TRD-AS1 expression was positively regulated by c-Myc.
• Enhanced TRD-AS1 levels correlated with increased OSCC cell migration and proliferation.
• TRD-AS1 influenced tumor metabolism, particularly acid metabolism.