Diagnostic efficacy of endoscopic ultrasound-guided fine needle aspiration cytology in pancreatic lesions

Endoscopic Ultrasound (EUS) guided needle aspiration cytology (FNAC) is a rapid, reliable diagnostic procedure used in various benign and malignant pancreatic lesions. The present study was aimed to determine the diagnostic accuracy of endoscopic ultrasound-guided needle aspiration cytology (EUS-FNAC) in diagnosing pancreatic lesions. To the best of our knowledge, the first study of this kind in eastern India. The current study was a hospital-based prospective study. The study was conducted in a tertiary care hospital of eastern India over a period of two year. A total of 67 cases of radiologically detected pancreatic lesions were studied. Pancreatic lesions were sampled by EUS-FNA and cytology reporting was done basing on Papanicolaou Society for assessment of cytology of pancreatobiliary system (PSC)as well as new WHO system of reporting 2022. A simultaneous needle biopsy(FNAB)was done to reach at a final histopathology diagnosis. The Cytology reports were compared with the corresponding histology reports as the latter is considered to be the gold standard. Diff-Quik / PAP/H Category II (negative for malignancy) cases were highest in number(n = 27),then were the Category VI( positive or malignant ) i.e. (n = 25).Sensitivity, specificity, PPV, NPV and diagnostic accuracy were 84.6%, 60%, 58%, 85.71% Sensitivity, specificity, PPV, NPV and diagnostic accuracy as87.5%, 82.8%, 82.3%, 87.8% &85.07%. EUS-FNA is an effective diagnostic procedure for differentiating malignant and benign pancreatic lesions. Hence, it is helpful for initiating an early management strategy.